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Cehny influenza vaccines for injection are generally killed virus vaccines and are allowed; however, intranasal influenza vaccines e. Flu-Mist are live attenuated vaccines, and pnline not allowed. Prior administration of intravesical BCG is allowed. Glucocorticoids for any purpose other than to modulate symptoms from an event of suspected immunologic etiology.

The use of physiologic doses of corticosteroids defined as 10 mg prednisone are acceptable, however site investigators should consult with the study chair for any dose higher than 10 mg puj. Dexamethasone 4 mg iv with chemotherapy to prevent nausea is allowed. Calgary adult chat must not have a major surgical procedure within 28 days prior to randomization. TURBT is not considered a major surgical procedure. Patients must not have received treatment with systemic immunosuppressive medications including, but not limited to, prednisone, cyclophosphamide, azathioprine, methotrexate, thalidomide, and anti-tumor pyu factor [anti-TNF] agents within 14 days prior to randomization.

Exceptions: Patients may have received acute, low dose, systemic immunosuppressant medications e. The use of inhaled corticosteroids and mineralocorticoids e. Physiological doses equivalent of 10 mg prednisone daily are allowed. Short term steroids given as antiemetic therapy, e. Patients must not have received a live, attenuated vaccine within 4 weeks sex chat brazil to randomization or anticipate that such a live, attenuated vaccine will be required while on protocol treatment and up to 5 months after the last dose of protocol treatment.

Inactivated influenza vaccination should be given during influenza season only approximately October to March. Patients must not receive live, attenuated influenza vaccine within 4 weeks prior to randomization or while on protocol treatment and up to 5 months after the last dose of protocol treatment. Patients must not have undergone prior allogeneic bone marrow transplantation or prior solid organ transplantation. Patients must not have clinically ificant liver disease that precludes patient from treatment regimens prescribed on the study including, but not limited to, active viral, alcoholic or other autoimmune hepatitis, cirrhosis or inherited liver disease.

Patient must not have history of idiopathic pulmonary fibrosis, pneumonitis including drug inducedorganizing pneumonia i. Patients must not have an active infection requiring oral or IV antibiotics within 14 days prior to randomization.